Population BRCA testing in Ashkenazi Jews reduces anxiety and does not adversely affect psychological health or quality of life
Study indicates that population‐based Ashkenazi Jewish BRCA testing does not adversely affect long‐term psychological wellbeing or quality‐of‐life, decreases anxiety and could identify up to 150% additional BRCA carriers.
81 Attitude towards and factors affecting uptake of population based BRCA testing in Ashkenazi Jews: a cohort study
BRCA testing in the Ashkenazi Jewish population shows high acceptability. Pre-test counselling increases awareness of disadvantages/limitations of BRCA-testing, influencing the final cost-benefit perception and decision-making of undergoing testing.
This study found unselected, high-risk multigene testing for all patients with BC to be extremely cost-effective compared with testing based on FH or clinical criteria for UK and US health systems. These findings support changing current policy to expand genetic testing to all women with BC.